Doebner modification

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English[edit]

Etymology[edit]

Named after O. Doebner, who published on the topic in 1902.

Proper noun[edit]

the Doebner modification

  1. (chemistry) A variant of Knoevenagel condensation in which one of the withdrawing groups on the nucleophile is a carboxylic acid, and the condensation product undergoes a subsequent decarboxylation step, the base being pyridine.
    Synonym: Doebner condensation
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