afucosylate

English

Etymology

From a- +‎ fucosylate.

Verb

afucosylate (third-person singular simple present afucosylates, present participle afucosylating, simple past and past participle afucosylated)

1. (transitive, biochemistry, rare) To remove a fucosyl group from.

   Antonym: fucosylate

   • 2015, Bauke Pauwels, Karin Jonstam, Claus Bachert, “Emerging biologics for the treatment of chronic rhinosinusitis”, in Expert Review of Clinical Immunology, volume 11, number 3, →DOI, →ISSN, page 355:

     By afucosylating benralizumab, it does not only binds^[sic] IL-5Rα with a higher affinity, which leads to a competitive inhibition of IL-5, but also induces active apoptosis by antibody-dependent cell-mediated cytotoxicity [13,61,62].

Related terms

• afucosylated