hypergranular
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English[edit]
Etymology[edit]
Adjective[edit]
hypergranular (not comparable)
- Excessively granular
- 2016 January 27, “Addition of Arsenic Trioxide into Induction Regimens Could Not Accelerate Recovery of Abnormality of Coagulation and Fibrinolysis in Patients with Acute Promyelocytic Leukemia”, in PLOS ONE[1], :
- It is characterized by an excess of abnormal hypergranular promyelocytes in the bone marrow and other hematopoietic organs, and chromosomal translocation t(15;17)(q22;q21) leading to fusion of the genes encoding promyelocytic leukemia protein(PML) and retinoic acid receptor alpha (RARα) to generate the PML-RARα oncoprotein [2 ].