misreplicate

English

Etymology

mis- +‎ replicate

Verb

misreplicate (third-person singular simple present misreplicates, present participle misreplicating, simple past and past participle misreplicated)

1. (transitive, intransitive, biochemistry, of DNA) To make an error during replication.
   • 1970, Michael Abercrombie, Jean Brachet, Thomas Joseph King, Advances in Morphogenesis - Volume 8, page 177:

     During cell division there is a probability that either or both of the master replicons will misreplicate and one of the daughter cells will be missing a master copy.

   • 1973, Alfred Marlyn Elliott, Biology of Tetrahymena, page 354:

     Thus when the second master unit begins to misreplicate, then in cells that still possess both units, the rate of misreplication becomes the same for both master units, even though they were initially lost at different rates.

   • 2011, Ian McDonald, Necroville:

     Transcription errors cause a tector to misreplicate into a form symbiotic with living cells.

   • 2013, Edward Schneider, The Genetics of Aging, page 18:

     It is important to realize that errors in protein synthesis may also result in altered DNA polymerase, which would misreplicate DNA, thereby injecting errors into the genome that would lead to clones of abnormal cells (Orgel, 1973).