oversialylated
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English[edit]
Etymology[edit]
over- + sialylated
Adjective[edit]
oversialylated (not comparable)
- Excessively sialylated
- 2015 November 17, “Loss of Cellular Sialidases Does Not Affect the Sialylation Status of the Prion Protein but Increases the Amounts of Its Proteolytic Fragment C1”, in PLOS ONE[1], :
- While it would be interesting to test whether prion disease is delayed in Neu1 knockout mice, these mice, unfortunately, do not have a sufficient lifespan, as they suffer from sialidosis, muscle degeneration and Alzheimer’s disease-like amyloidogenic processing of an oversialylated amyloid precursor protein in lysosomes [60, 63, 64 ].