tetrathiolate
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English[edit]
Etymology[edit]
Noun[edit]
tetrathiolate (plural tetrathiolates)
- Any compound containing four thiolate groups
- 2016 March 4, “Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung”, in PLOS ONE[1], :
- Increased uncoupling of eNOS due to different factors—elevated levels of ADMA [53, 54 ], reduced association with Hsp90 [55 ], decreased tetrahydrobiopterin levels [56 ], oxidation of tetrathiolate cluster by hydrogen peroxide, nitric oxide or peroxynitrite [57 –59 ]—reduce consumption of arginine through the NO pathway leading to vasoconstriction in pulmonary artery [54, 60 ].